{"id":854,"date":"2010-12-04T08:16:58","date_gmt":"2010-12-03T23:16:58","guid":{"rendered":"http:\/\/www.shinondo.com\/?p=854"},"modified":"2013-08-02T13:37:08","modified_gmt":"2013-08-02T04:37:08","slug":"%e5%85%a8%e8%ba%ab%e6%80%a7%e3%82%a8%e3%83%aa%e3%83%86%e3%83%9e%e3%83%88%e3%83%bc%e3%83%87%e3%82%b9%ef%bc%88sle%ef%bc%89","status":"publish","type":"post","link":"https:\/\/www.shinondo.com\/?p=854","title":{"rendered":"\u5168\u8eab\u6027\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\uff08SLE\uff09"},"content":{"rendered":"<p>\u3000\u5168\u8eab\u6027\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\uff08\u4ee5\u4e0bSLE\uff09\u306e\u75c5\u614b\u306b\u3064\u3044\u3066<\/p>\n<p>\u81a0\u539f\u75c5\uff08connective tissue disease\uff09\u306e\u4ee3\u8868\u7684\u306a\u75be\u60a3\u3067\u3042\u308b<br \/>\n\u76ae\u819a\u3001\u95a2\u7bc0\u3001\u6f3f\u819c\u3001\u5fc3\u3001\u814e\u3001\u80ba\u3001\u4e2d\u67a2\u795e\u7d4c\u306a\u3069\u304c\u3001\u6025\u6027\u53ca\u3073\u6162\u6027\u306e\u75c7\u72b6\u3092\u7e70\u308a\u8fd4\u3057\u306a\u304c\u3089<br \/>\n\u7d50\u5408\u7d44\u7e54\u3092\u7cfb\u7d71\u7684\u306b\u5192\u3057\u3001\u3064\u3044\u306b\u306f\u30d5\u30a3\u30d6\u30ea\u30ce\u30a4\u30c9\u5909\u6027\uff08fibrinoid degenerration\uff09\u3092\u8d77\u3053\u3059\u75be\u60a3\u3067\u3042\u308b<\/p>\n<pre>\u30d5\u30a3\u30d6\u30ea\u30ce\u30a4\u30c9\u5909\u6027\u3068\u306f\u8840\u7ba1\u3084\u7d50\u5408\u7d44\u7e54\u306b\u5909\u6027\u3057\u305f\u30d5\u30a3\u30d6\u30ea\u30f3\u3092\u4e3b\u4f53\u3068\u3059\u308b\r\n\u7a2e\u3005\u306e\u8840\u6f3f\u6210\u5206\u3088\u308a\u306a\u308b\u7269\u8cea\u304c\u6ef2\u307f\u8fbc\u307f\u5f62\u6210\u3055\u308c\u308b\u5909\u6027\u3002\r\n\u540c\u7fa9\u8a9e\u3068\u3057\u3066\u985e\u7dda\u7dad\u7d20\u5909\u6027\u3001\u7dda\u7dad\u7d20\u69d8\u5909\u6027\u3001\u30d5\u30a3\u30d6\u30ea\u30f3\u69d8\u5909\u6027\u3002<\/pre>\n<pre>\u539f\u56e0\u3000\r\n\u3000\u3000\u3000\u3000\u4e0d\u660e\u3067\u3042\u308b\u3002\u3057\u304b\u3057\u3001\u907a\u4f1d\u3001\u74b0\u5883\u56e0\u5b50\u3001\u30a6\u30a4\u30eb\u30b9\u306a\u3069\u304c\u8907\u96d1\u306b\u7d61\u307f\u5408\u3044\u3001\r\n        \u514d\u75ab\u7570\u5e38\u304c\u8d77\u3053\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u8a00\u308f\u308c\u3066\u3044\u308b\u3002\r\n\u3000\u3000\u3000\u3000\r\n\u3000\u3000\u3000\u3000\u767a\u75c7\u306e\u305d\u3082\u305d\u3082\u306e\u539f\u56e0\u306b\u3064\u3044\u3066\u306f\u3001\u4eca\u306e\u3068\u3053\u308d\u5206\u304b\u3063\u3066\u3044\u306a\u3044\u3002\r\n\u3000\u3000\u3000\u3000\u73fe\u5728\u306e\u4eee\u8aac\u3067\u306f\u3001\u8907\u6570\u306e\u907a\u4f1d\u56e0\u5b50\u3068\u74b0\u5883\u56e0\u5b50\u306e\u53cc\u65b9\u304c\u95a2\u9023\u3059\u308b\u3068\r\n        \u8003\u3048\u3089\u308c\u3066\u304a\u308a\u3001\u53cc\u751f\u5150\u7814\u7a76\u306e\u7d50\u679c\u306a\u3069\u304b\u3089\u306f\u540c\u69d8\u306e\u591a\u56e0\u5b50\u907a\u4f1d\u75be\u60a3\u3068\u8003\u3048\u3089\u308c\u308b\u3002\r\n\u3000\u3000\u3000  \u7cd6\u5c3f\u75c5\u3084\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u306a\u3069\u3068\u6bd4\u8f03\u3059\u308b\u3068\u907a\u4f1d\u56e0\u5b50\u306e\u5f71\u97ff\u306f\u5f37\u3044\u3068\u601d\u308f\u308c\u308b\u3002\r\n\u3000\u3000\u3000\u3000\r\n\u3000\u3000\u3000  \u5f37\u3044\u65e5\u5149\u3078\u306e\u66b4\u9732\u5f8c\u306bSLE\u3092\u767a\u75c7\u3057\u305f\u308a\u3001\r\n\u3000\u3000\u3000  SLE\u75c5\u52e2\u306e\u5897\u60aa\u304c\u898b\u3089\u308c\u308b\u4e8b\u304b\u3089\u3001\u7d2b\u5916\u7dda\u7167\u5c04\u304c\u514d\u75ab\u7cfb\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u3092\r\n        \u767a\u75c7\u539f\u56e0\u306e\u4e00\u3064\u3068\u8003\u3048\u308b\u8aac\u3082\u3042\u308b\u3000\u3000\u3000\u3000<\/pre>\n<pre>\u75c7\u72b6\u3000\r\n\u3000\u3000\u3000\u3000\u767a\u71b1\u3001\u95a2\u7bc0\u75db\u3001\u9854\u9762\u3084\u624b\u6307\u306e\u7d05\u6591\u3001\u30ec\u30a4\u30ce\u30fc\u75c7\u72b6\u306a\u3069\u304c\u767a\u75c7\u65e9\u671f\u75c7\u72b6\u3068\u3057\u3066\u591a\u304f\u3001\r\n        \u95a2\u7bc0\u708e\u3001\u8776\u5f62\u7d05\u6591\u3001\u814e\u708e\u3001\u795e\u7d4c\uff08\u7cbe\u795e\uff09\u75c7\u72b6\u3001\u3084\u75d9\u6523\u306a\u3069\u306e\u4e2d\u67a2\u75c7\u72b6\u3001\r\n\u3000\u3000\u3000\u3000\u80f8\u819c\u708e\u3001\u5fc3\u819c\u708e\u306a\u3069\u304c\u4e3b\u8981\u75c7\u72b6\u3067\u3042\u308b\u3002\r\n\r\n\u3000<\/pre>\n<pre>\u3000\u3000\u3044\u304f\u3064\u304b\u306e\u4ed6\u306e\u81ea\u5df1\u514d\u75ab\u75be\u60a3(Autoimmune disease)\u3068\u540c\u69d8\u306b\u3001\r\n\u767a\u751f\u983b\u5ea6\u306f\u5727\u5012\u7684\u306b\u5973\u6027\u306b\u591a\u304f\u3001\u307e\u305f\u82e5\u5e74\u5c64\u306b\u983b\u767a\u3059\u308b\u3002\r\n\u7537\u5973\u6bd4\u306f1:10\u7a0b\u5ea6\u3067\u3001\u307e\u305f\u307b\u3068\u3093\u3069\u306f15-40\u6b73\u306e\u5b50\u4f9b\u3092\u7523\u3081\u308b\u3088\u3046\u306a\u5e74\u9f62\u306b\u767a\u75c7\u3059\u308b\u305f\u3081\u3001\r\n\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\uff08Estrogen\uff09\u306a\u3069\u306e\u5973\u6027\u30db\u30eb\u30e2\u30f3\u306e\u767a\u75c7\u3078\u306e\u95a2\u4e0e\u304c\u7591\u308f\u308c\u3066\u3044\u308b\u3002\r\n\u3000\r\n\u3000\u982c\u304b\u3089\u9f3b\u306b\u304b\u3051\u3066\u304b\u304b\u308b\u4e18\u75b9\u72b6\u306e\u7d05\u6591\u3067\u3042\u308b\u8776\u5f62\u7d05\u6591\u306f\u672c\u75c7\u306b\u975e\u5e38\u306b\u7279\u7570\u7684\u306a\u75c7\u72b6\u3067\u3042\u308b\u304c\u3001\r\n\u611f\u5ea6\u306f\u9ad8\u304f\u306a\u304f\u3001\u534a\u5206\u7a0b\u5ea6\u3067\u3042\u308b\u3002\u72fc\u306e\u3088\u3046\u306a\u5916\u898b\u3092\u5448\u3059\u308b\u3068\u3044\u3046\u304c\u3001\r\n\u305d\u3053\u307e\u3067\u81f3\u308b\u4f8b\u306f\u7a00\u3002\u305d\u306e\u307b\u304b\u5186\u677f\u72b6\u30eb\u30fc\u30d7\u30b9\u3001\u4e9c\u6025\u6027\u76ae\u819a\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\u3001\r\nlupus profundus\u306a\u3069\u3068\u3044\u3063\u305f\u76ae\u819a\u75c7\u72b6\u304c\u8d77\u3053\u308a\u3046\u308b\r\n\u3000\r\n\u3000\u6642\u306b\u306f\u3001\u8155\u304b\u3089\u624b\u306e\u6307\u5148\u307e\u3067\u3082\u3057\u304f\u306f\u811a\u304b\u3089\u8db3\u306e\u6307\u5148\u307e\u3067\u76ae\u819a\u306b\u6d6e\u304b\u3076\u8840\u7ba1\u304c\u7db2\u76ee\u72b6\u306b\u306a\u308b\u3002\r\n\u84bc\u767d\u8272\u306b\u306a\u308b\u3060\u3051\u3084\u3001\u77e5\u899a\u920d\u9ebb\u3084\u75bc\u75db\u306a\u3069\u306e\u75c7\u72b6\u3092\u793a\u3059\u5834\u5408\u3082\u3042\u308b\u3002\r\n\u3000<span style=\"text-decoration: underline;\">\u79cb\u304b\u3089\u51ac<\/span>\u306b\u304b\u3051\u3066\u3001\u307e\u305f\u3001\u6625\u5148\u306e\u51b7\u3048\u8fbc\u3093\u3060\u6642\u306b\u591a\u304f\u307f\u3089\u308c\u3001\u91cd\u75c7\u306e\u5834\u5408\u3001\r\n\u6307\u5148\u306e\u6f70\u760d\u3084\u5909\u5f62\u3092\u8d77\u3053\u3059\u3068\u3082\u7a00\u306b\u3042\u308b\u3002<\/pre>\n<pre>\u3000\u30ec\u30a4\u30ce\u30fc\u75c5\uff08Raynaud\uff09\u3068\u306f\u3001\u5bd2\u51b7\u6642\u3084\u51b7\u6c34\u306b\u3064\u304b\u3063\u305f\u3068\u304d\u306b\u56db\u80a2\u672b\u68a2\u90e8\u3001\r\n\u3068\u304f\u306b\u4e21\u624b\u6307\u304c\u5bfe\u79f0\u7684\u306b\u75db\u307f\u3001\u3057\u3073\u308c\u611f\u3068\u3068\u3082\u306b\u84bc\u767d\u3001\r\n\u3042\u308b\u3044\u306f\u30c1\u30a2\u30ce\u30fc\u30bc\u00a0(\u30c9\u30a4\u30c4\u8a9e: Zyanose\u3001\u82f1\u8a9e: cyanosis)\r\n\u306a\u3069\u306e\u865a\u8840\u75c7\u72b6\u3092\u304d\u305f\u3059\u5834\u5408\u3067\u3001\u82e5\u5e74\u5973\u5b50\u306b\u591a\u767a\u3059\u308b\u3002\r\n\u539f\u56e0\u306f\u660e\u3089\u304b\u3067\u306a\u3044\u3002\u3000\u3000\u3000\u3000\r\n\u672c\u75c7\u306e\uff14\u4eba\u306b\uff11\u4eba\u306b\u30ec\u30a4\u30ce\u30fc\u75c7\u306f\u307f\u3089\u308c\u308b\u3002\u3000<\/pre>\n<pre>\u3000\r\n\r\n\u4e3b\u306a\u691c\u67fb\u6cd5\u3000\r\n\u3000\u3000\u3000\u3000\u3000\u3000\u6b63\u7403\u6027\u3001\u751f\u8272\u7d20\u6027\u306e\u8ca7\u8840\u3068\u767d\u8840\u7403\u306e\u6e1b\u5c11\u3001\r\n\u3000\u3000\u3000\u3000\u3000\u3000\u7279\u306b\u30ea\u30f3\u30d1\u7403\u304c\u5c11\u306a\u304f\u306a\u3063\u3066\u3044\u308b\u3002\r\n\u3000\u3000\u3000\u3000\u3000\u3000\u8840\u6f3f\u677f\u3082\uff15\uff5e\uff11\uff10\u4e07\u3068\u6e1b\u5c11\u3057\u3001\u30d7\u30ed\u30c8\u30ed\u30f3\u30d3\u30f3\u3068\r\n\u3000\u3000\u3000\u3000\u3000\u3000\u90e8\u5206\u30c8\u30ed\u30f3\u30dc\u30d7\u30e9\u30b9\u30c1\u30f3\u6642\u9593\u304c\u5ef6\u9577\u3059\u308b\u3002\r\n\u3000\u3000\u3000\u3000\u3000\u3000\u307e\u305f\u3001\u6297DNA\u6297\u4f53\u3084\u6297S\uff4d\u6297\u4f53\u304c\u967d\u6027\u3001\u8840\u4e2d\u514d\u75ab\u8907\u5408\u4f53\u304c\u9ad8\u5024\u3001\r\n\u3000\u3000\u3000\u3000\u3000\u3000\u8840\u4e2d\u88dc\u4f53\u4fa1\u304c\u4f4e\u5024\u3092\u793a\u3059\u3002\r\n\r\n\u3000\u3000\r\n\u3000\u3000\u3000\u3000<\/pre>\n<p>\u53c2\u8003\u6587\u732e<br \/>\n\u5ee3\u5ddd\u66f8\u5e97\u3000\u533b\u7642\u85ac\u5b66\uff08\u75c5\u6c17\u3068\u85ac\uff09<br \/>\n\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u75be\u75c5\u3068\u75c5\u614b<\/p>\n<p>\u3066\u3093\u304b\u3093\u306b\u3064\u3044\u3066\u2193<br \/>\n<a href=\"https:\/\/www.shinondo.com\/2010\/11\/03\/\">https:\/\/www.shinondo.com\/2010\/11\/03\/<\/a>\u3066\u3093\u304b\u3093\u306e\u75c5\u614b<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3000\u5168\u8eab\u6027\u30a8\u30ea\u30c6\u30de\u30c8\u30fc\u30c7\u30b9\uff08\u4ee5\u4e0bSLE\uff09\u306e\u75c5\u614b\u306b\u3064\u3044\u3066 \u81a0\u539f\u75c5\uff08connective tissue disease\uff09\u306e\u4ee3\u8868\u7684\u306a\u75be\u60a3\u3067\u3042\u308b \u76ae\u819a\u3001\u95a2\u7bc0\u3001\u6f3f\u819c\u3001\u5fc3\u3001\u814e\u3001\u80ba\u3001\u4e2d\u67a2\u795e\u7d4c\u306a\u3069\u304c\u3001\u6025\u6027\u53ca\u3073\u6162\u6027\u306e\u75c7\u72b6\u3092\u7e70\u308a\u8fd4\u3057\u306a\u304c\u3089 \u7d50 [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"vkexunit_cta_each_option":""},"categories":[1],"tags":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.shinondo.com\/index.php?rest_route=\/wp\/v2\/posts\/854"}],"collection":[{"href":"https:\/\/www.shinondo.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.shinondo.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.shinondo.com\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.shinondo.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=854"}],"version-history":[{"count":10,"href":"https:\/\/www.shinondo.com\/index.php?rest_route=\/wp\/v2\/posts\/854\/revisions"}],"predecessor-version":[{"id":2714,"href":"https:\/\/www.shinondo.com\/index.php?rest_route=\/wp\/v2\/posts\/854\/revisions\/2714"}],"wp:attachment":[{"href":"https:\/\/www.shinondo.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=854"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.shinondo.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=854"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.shinondo.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=854"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}